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Coordination of Eukaryotic Translation Elongation Factor 1A (eEF1A) Function in Actin Organization and Translation Elongation by the Guanine Nucleotide Exchange Factor eEF1Bα

Eukaryotic translation elongation factor 1A (eEF1A) both shuttles aminoacyl-tRNA (aa-tRNA) to the ribosome and binds and bundles actin. A single domain of eEF1A is proposed to bind actin, aa-tRNA and the guanine nucleotide exchange factor eEF1Bα. We show that eEF1Bα has the ability to disrupt eEF1A-...

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Bibliografiske detaljer
Main Authors: Pittman, Yvette R., Kandl, Kimberly, Lewis, Marcus, Valente, Louis, Kinzy, Terri Goss
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640982/
https://ncbi.nlm.nih.gov/pubmed/19095653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807945200
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