Guanine Nucleotide Exchange Factor Independence of the G-protein eEF1A through Novel Mutant Forms and Biochemical Properties

Most G-proteins require a guanine nucleotide exchange factor (GEF) to regulate a variety of critical cellular processes. Interestingly, a small number of G-proteins switch between the active and inactive forms without a GEF. Translation elongation factor 1A (eEF1A) normally requires the GEF eEF1Bα t...

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Detalles Bibliográficos
Autores principales: Ozturk, Sedide B., Kinzy, Terri Goss
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517005/
https://ncbi.nlm.nih.gov/pubmed/18562321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801095200
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