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Caveolin-1 alters Ca(2+) signal duration through specific interaction with the Gα(q) family of G proteins

Caveolae are membrane domains having caveolin-1 (Cav1) as their main structural component. Here, we determined whether Cav1 affects Ca(2+) signaling through the Gα(q)-phospholipase-Cβ (PLCβ) pathway using Fischer rat thyroid cells that lack Cav1 (FRTcav(-)) and a sister line that forms caveolae-like...

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Autors principals: Sengupta, Parijat, Philip, Finly, Scarlata, Suzanne
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639659/
https://ncbi.nlm.nih.gov/pubmed/18397999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.020081
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