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Gα(q) Binds Two Effectors Separately in Cells: Evidence for Predetermined Signaling Pathways

G-proteins transduce signals along diverse pathways, but the factors involved in pathway selection are largely unknown. Here, we have studied the ability of Gα(q) to select between two effectors—mammalian inositide-specific phospholipase Cβ (PLCβ) and phosphoinositide-3-kinase (PI3K)—in human embryo...

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Bibliographic Details
Main Authors: Golebiewska, Urszula, Scarlata, Suzanne
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517025/
https://ncbi.nlm.nih.gov/pubmed/18515384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.129353
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