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Evidence for a Second, High Affinity Gβγ Binding Site on Gα(i1)(GDP) Subunits
It is well known that Gα(i1)(GDP) binds strongly to Gβγ subunits to form the Gα(i1)(GDP)-Gβγ heterotrimer, and that activation to Gα(i1)(GTP) results in conformational changes that reduces its affinity for Gβγ subunits. Previous studies of G protein subunit interactions have used stoichiometric amou...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719327/ https://ncbi.nlm.nih.gov/pubmed/19369247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006585 |
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