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Determination of the Activation Volume of PLCβ by Gβγ-Subunits through the Use of High Hydrostatic Pressure

Activation of phospholipase Cβ (PLCβ) by G-proteins results in increased intracellular Ca(2+) and activation of protein kinase C. We have previously found that activated PLCβ-Gβγ complex can be rapidly deactivated by Gα(GDP) subunits without dissociation, which led to the suggestion that Gα(GDP) bin...

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Detalhes bibliográficos
Autor principal: Scarlata, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305381/
https://ncbi.nlm.nih.gov/pubmed/15665133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055715
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