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A Dynamic Model of Membrane-Bound Phospholipase Cβ2 Activation by Gβγ Subunits
Phospholipase C (PLC) β2, a well studied member of the family of enzymes that catalyze the hydrolysis of the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP(2)) into secondary messengers, can be activated by the Gβγ subunits of heterotrimeric G-proteins in a manner that depends on the pres...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164327/ https://ncbi.nlm.nih.gov/pubmed/21693623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073403 |
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