Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms

Prostaglandin D(2) (PGD(2)) and its receptor chemoattractant receptor homologous molecule expressed on T(h)2 cells (CRTH2) have been implicated in the pathogenesis of numerous allergic diseases. We investigated the role of PGD(2) and CRTH2 in allergic cutaneous inflammation by using a highly potent...

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Bibliografiska uppgifter
Huvudupphovsmän: Boehme, Stefen A., Chen, Edward P., Franz-Bacon, Karin, Šášik, Roman, Sprague, L. James, Ly, Tai Wei, Hardiman, Gary, Bacon, Kevin B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Original Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638839/
https://ncbi.nlm.nih.gov/pubmed/19066315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn118
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