MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung inflammation resulting in a progressive decline in lung function whose principle cause is cigarette smoke. MAP3K19 is a novel kinase expressed predominantly by alveolar and interstitial macrophage...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Boehme, Stefen A., Franz-Bacon, Karin, Ludka, John, DiTirro, Danielle N., Ly, Tai Wei, Bacon, Kevin B.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147866/
https://ncbi.nlm.nih.gov/pubmed/27935962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167169
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