Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice

INTRODUCTION: Airway surface dehydration, caused by an imbalance between secretion and absorption of ions and fluid across the epithelium and/or increased epithelial mucin secretion, impairs mucociliary clearance. Recent evidence suggests that this mechanism may be implicated in chronic obstructive...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Seys, Leen J. M., Verhamme, Fien M., Dupont, Lisa L., Desauter, Elke, Duerr, Julia, Seyhan Agircan, Ayca, Conickx, Griet, Joos, Guy F., Brusselle, Guy G., Mall, Marcus A., Bracke, Ken R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466573/
https://ncbi.nlm.nih.gov/pubmed/26066648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129897
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