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Regulation of inhibitory synaptic transmission by a conserved atypical AP2 interaction within GABA(A) receptor β and γ subunits

The number of surface and synaptic GABA(A) receptors is an important determinant of inhibitory synapse strength. Surface receptor number is in part controlled by removal of receptors from the membrane by interaction with the clathrin adaptor AP2. Here we demonstrate that there are two binding sites...

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書誌詳細
主要な著者: Smith, Katharine R., McAinsh, Kristina, Chen, Guojun, Arancibia-Carcamo, I. Lorena, Haucke, Volker, Yan, Zhen, Moss, Stephen J., Kittler, Josef T.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638071/
https://ncbi.nlm.nih.gov/pubmed/18662706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.06.072
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