Regulation of inhibitory synaptic transmission by a conserved atypical AP2 interaction within GABA(A) receptor β and γ subunits

The number of surface and synaptic GABA(A) receptors is an important determinant of inhibitory synapse strength. Surface receptor number is in part controlled by removal of receptors from the membrane by interaction with the clathrin adaptor AP2. Here we demonstrate that there are two binding sites...

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Main Authors: Smith, Katharine R., McAinsh, Kristina, Chen, Guojun, Arancibia-Carcamo, I. Lorena, Haucke, Volker, Yan, Zhen, Moss, Stephen J., Kittler, Josef T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638071/
https://ncbi.nlm.nih.gov/pubmed/18662706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.06.072
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