Regulation of inhibitory synaptic transmission by a conserved atypical AP2 interaction within GABA(A) receptor β and γ subunits

The number of surface and synaptic GABA(A) receptors is an important determinant of inhibitory synapse strength. Surface receptor number is in part controlled by removal of receptors from the membrane by interaction with the clathrin adaptor AP2. Here we demonstrate that there are two binding sites...

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Bibliographic Details
Main Authors: Smith, Katharine R., McAinsh, Kristina, Chen, Guojun, Arancibia-Carcamo, I. Lorena, Haucke, Volker, Yan, Zhen, Moss, Stephen J., Kittler, Josef T.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638071/
https://ncbi.nlm.nih.gov/pubmed/18662706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.06.072
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