Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABA(A) receptor γ2 subunit

The regulation of the number of γ2-subunit-containing GABA(A) receptors (GABA(A)Rs) present at synapses is critical for correct synaptic inhibition and animal behavior. This regulation occurs, in part, by the controlled removal of receptors from the membrane in clathrin-coated vesicles, but it remai...

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Autors principals: Kittler, Josef T., Chen, Guojun, Kukhtina, Viktoria, Vahedi-Faridi, Ardeschir, Gu, Zhenglin, Tretter, Verena, Smith, Katharine R., McAinsh, Kristina, Arancibia-Carcamo, I. Lorena, Saenger, Wolfram, Haucke, Volker, Yan, Zhen, Moss, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265186/
https://ncbi.nlm.nih.gov/pubmed/18305175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707920105
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