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Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating γ-aminobutyric acid type A receptor membrane trafficking

γ-Aminobutyric acid type A receptors (GABA(A)Rs) are the major sites of fast synaptic inhibition in the brain. An essential determinant for the efficacy of synaptic inhibition is the regulation of GABA(A)R cell surface stability. Here, we have examined the regulation of GABA(A)R endocytic sorting, a...

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Bibliographische Detailangaben
Hauptverfasser: Kittler, Josef T., Thomas, Philip, Tretter, Verena, Bogdanov, Yuri D., Haucke, Volker, Smart, Trevor G., Moss, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515122/
https://ncbi.nlm.nih.gov/pubmed/15310851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401860101
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