Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating γ-aminobutyric acid type A receptor membrane trafficking

γ-Aminobutyric acid type A receptors (GABA(A)Rs) are the major sites of fast synaptic inhibition in the brain. An essential determinant for the efficacy of synaptic inhibition is the regulation of GABA(A)R cell surface stability. Here, we have examined the regulation of GABA(A)R endocytic sorting, a...

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Detalhes bibliográficos
Main Authors: Kittler, Josef T., Thomas, Philip, Tretter, Verena, Bogdanov, Yuri D., Haucke, Volker, Smart, Trevor G., Moss, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515122/
https://ncbi.nlm.nih.gov/pubmed/15310851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401860101
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