Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating γ-aminobutyric acid type A receptor membrane trafficking

γ-Aminobutyric acid type A receptors (GABA(A)Rs) are the major sites of fast synaptic inhibition in the brain. An essential determinant for the efficacy of synaptic inhibition is the regulation of GABA(A)R cell surface stability. Here, we have examined the regulation of GABA(A)R endocytic sorting, a...

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Autors principals: Kittler, Josef T., Thomas, Philip, Tretter, Verena, Bogdanov, Yuri D., Haucke, Volker, Smart, Trevor G., Moss, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC515122/
https://ncbi.nlm.nih.gov/pubmed/15310851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401860101
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