NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells

Putative functions of the cellular prion protein, PrP(C), include resistance to oxidative stress, copper uptake, cell adhesion, and cell signaling. Here, we report NADPH oxidase-dependent reactive oxygen species (ROS) production and extracellular regulated kinases 1/2 (ERK1/2) phosphorylation on PrP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schneider, Benoît, Mutel, Vincent, Pietri, Mathéa, Ermonval, Myriam, Mouillet-Richard, Sophie, Kellermann, Odile
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC263804/
https://ncbi.nlm.nih.gov/pubmed/14597699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235648100
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