NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells

Putative functions of the cellular prion protein, PrP(C), include resistance to oxidative stress, copper uptake, cell adhesion, and cell signaling. Here, we report NADPH oxidase-dependent reactive oxygen species (ROS) production and extracellular regulated kinases 1/2 (ERK1/2) phosphorylation on PrP...

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Bibliographische Detailangaben
Hauptverfasser: Schneider, Benoît, Mutel, Vincent, Pietri, Mathéa, Ermonval, Myriam, Mouillet-Richard, Sophie, Kellermann, Odile
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC263804/
https://ncbi.nlm.nih.gov/pubmed/14597699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235648100
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