Protective role of cellular prion protein against TNFα-mediated inflammation through TACE α-secretase

Although cellular prion protein PrP(C) is well known for its implication in Transmissible Spongiform Encephalopathies, its functions remain elusive. Combining in vitro and in vivo approaches, we here show that PrP(C) displays the intrinsic capacity to protect neuronal cells from a pro-inflammatory T...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Ezpeleta, Juliette, Boudet-Devaud, François, Pietri, Mathéa, Baudry, Anne, Baudouin, Vincent, Alleaume-Butaux, Aurélie, Dagoneau, Nathalie, Kellermann, Odile, Launay, Jean-Marie, Schneider, Benoit
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550509/
https://ncbi.nlm.nih.gov/pubmed/28794434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08110-x
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares