Protective role of cellular prion protein against TNFα-mediated inflammation through TACE α-secretase

Although cellular prion protein PrP(C) is well known for its implication in Transmissible Spongiform Encephalopathies, its functions remain elusive. Combining in vitro and in vivo approaches, we here show that PrP(C) displays the intrinsic capacity to protect neuronal cells from a pro-inflammatory T...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ezpeleta, Juliette, Boudet-Devaud, François, Pietri, Mathéa, Baudry, Anne, Baudouin, Vincent, Alleaume-Butaux, Aurélie, Dagoneau, Nathalie, Kellermann, Odile, Launay, Jean-Marie, Schneider, Benoit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550509/
https://ncbi.nlm.nih.gov/pubmed/28794434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08110-x
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