A carregar...
Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation
In prion diseases, synapse dysfunction, axon retraction and loss of neuronal polarity precede neuronal death. The mechanisms driving such polarization defects, however, remain unclear. Here, we examined the contribution of RhoA-associated coiled-coil containing kinases (ROCK), key players in neurito...
Na minha lista:
| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524729/ https://ncbi.nlm.nih.gov/pubmed/26241960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005073 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|