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The Cellular Prion Protein Interacts with the Tissue Non-Specific Alkaline Phosphatase in Membrane Microdomains of Bioaminergic Neuronal Cells

BACKGROUND: The cellular prion protein, PrP(C), is GPI anchored and abundant in lipid rafts. The absolute requirement of PrP(C) in neurodegeneration associated to prion diseases is well established. However, the function of this ubiquitous protein is still puzzling. Our previous work using the 1C11...

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Detalhes bibliográficos
Main Authors: Ermonval, Myriam, Baudry, Anne, Baychelier, Florence, Pradines, Elodie, Pietri, Mathéa, Oda, Kimimitsu, Schneider, Benoît, Mouillet-Richard, Sophie, Launay, Jean-Marie, Kellermann, Odile
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715859/
https://ncbi.nlm.nih.gov/pubmed/19652718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006497
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