NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells

Putative functions of the cellular prion protein, PrP(C), include resistance to oxidative stress, copper uptake, cell adhesion, and cell signaling. Here, we report NADPH oxidase-dependent reactive oxygen species (ROS) production and extracellular regulated kinases 1/2 (ERK1/2) phosphorylation on PrP...

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Detalhes bibliográficos
Main Authors: Schneider, Benoît, Mutel, Vincent, Pietri, Mathéa, Ermonval, Myriam, Mouillet-Richard, Sophie, Kellermann, Odile
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC263804/
https://ncbi.nlm.nih.gov/pubmed/14597699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235648100
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