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Inducible Nitric Oxide Synthase Inhibitor SD-3651 Reduces Proteinuria in MRL/lpr Mice Deficient in the NOS2 Gene
Several studies have demonstrated the effectiveness of arginine analog nitric oxide synthase (NOS) inhibitor therapy in preventing and treating murine lupus nephritis. However, MRL/MpJ-FAS(lpr) (MRL/lpr) mice lacking a functional NOS2 (inducible NOS [iNOS]) gene (NOS2(−/−)) develop proliferative glo...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637653/ https://ncbi.nlm.nih.gov/pubmed/18797415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.231/JIM.0b013e3181889e13 |
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