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Inducible Nitric Oxide Synthase Inhibitor SD-3651 Reduces Proteinuria in MRL/lpr Mice Deficient in the NOS2 Gene

Several studies have demonstrated the effectiveness of arginine analog nitric oxide synthase (NOS) inhibitor therapy in preventing and treating murine lupus nephritis. However, MRL/MpJ-FAS(lpr) (MRL/lpr) mice lacking a functional NOS2 (inducible NOS [iNOS]) gene (NOS2(−/−)) develop proliferative glo...

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Hlavní autoři: Njoku, Chinedu, Self, Sally E., Ruiz, Philip, Hofbauer, Ann F., Gilkeson, Gary S., Oates, Jim C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637653/
https://ncbi.nlm.nih.gov/pubmed/18797415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.231/JIM.0b013e3181889e13
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