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Vascular Protection by Tetrahydrobiopterin: Progress and Therapeutic Prospects

Tetrahydrobiopterin (BH4) is an essential co-factor required for the activity of endothelial nitric oxide synthase (eNOS). Suboptimal concentrations of BH4 in the endothelium reduce the biosynthesis of nitric oxide (NO), thus contributing to the pathogenesis of vascular endothelial dysfunction. Supp...

詳細記述

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書誌詳細
主要な著者: Katusic, Zvonimir S., d’Uscio, Livius, Nath, Karl A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637534/
https://ncbi.nlm.nih.gov/pubmed/19042039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.10.003
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