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Vascular Protection by Tetrahydrobiopterin: Progress and Therapeutic Prospects
Tetrahydrobiopterin (BH4) is an essential co-factor required for the activity of endothelial nitric oxide synthase (eNOS). Suboptimal concentrations of BH4 in the endothelium reduce the biosynthesis of nitric oxide (NO), thus contributing to the pathogenesis of vascular endothelial dysfunction. Supp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637534/ https://ncbi.nlm.nih.gov/pubmed/19042039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.10.003 |
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