Ploidy Reductions in Murine Fusion-Derived Hepatocytes

We previously showed that fusion between hepatocytes lacking a crucial liver enzyme, fumarylacetoacetate hydrolase (FAH), and wild-type blood cells resulted in hepatocyte reprogramming. FAH expression was restored in hybrid hepatocytes and, upon in vivo expansion, ameliorated the effects of FAH defi...

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Autores principales: Duncan, Andrew W., Hickey, Raymond D., Paulk, Nicole K., Culberson, Andrew J., Olson, Susan B., Finegold, Milton J., Grompe, Markus
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636893/
https://ncbi.nlm.nih.gov/pubmed/19229314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000385
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