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Ploidy Reductions in Murine Fusion-Derived Hepatocytes
We previously showed that fusion between hepatocytes lacking a crucial liver enzyme, fumarylacetoacetate hydrolase (FAH), and wild-type blood cells resulted in hepatocyte reprogramming. FAH expression was restored in hybrid hepatocytes and, upon in vivo expansion, ameliorated the effects of FAH defi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2636893/ https://ncbi.nlm.nih.gov/pubmed/19229314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000385 |
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