VectorMOD: Method for Bottom-Up Proteomic Characterization of rAAV Capsid Post-Translational Modifications and Vector Impurities

por Rumachik, Neil G., Malaker, Stacy A., Paulk, Nicole K.
Publicado no Front Immunol (2021)

AAV-Mediated Gene Targeting Is Significantly Enhanced by Transient Inhibition of Nonhomologous End Joining or the Proteasome In Vivo

por Paulk, Nicole K., Loza, Laura Marquez, Finegold, Milton J., Grompe, Markus
Publicado em 2012

Adeno-Associated Virus Gene Repair Corrects a Mouse Model of Hereditary Tyrosinemia In Vivo

por Paulk, Nicole K., Wursthorn, Karsten, Wang, Zhongya, Finegold, Milton J., Kay, Mark A., Grompe, Markus
Publicado em 2010

Ploidy Reductions in Murine Fusion-Derived Hepatocytes

por Duncan, Andrew W., Hickey, Raymond D., Paulk, Nicole K., Culberson, Andrew J., Olson, Susan B., Finegold, Milton J., Grompe, Markus
Publicado em 2009

Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings

por Maynard, Lucy H., Smith, Olivia, Tilmans, Nicolas P., Tham, Eleonore, Hosseinzadeh, Shayan, Tan, Weilun, Leenay, Ryan, May, Andrew P., Paulk, Nicole K.
Publicado no Hum Gene Ther Methods (2019)

An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging

por Oh, Younghee, Park, Yunhee, Cho, Julia H., Wu, Haodi, Paulk, Nicole K., Liu, Lan Xiang, Kim, Namdoo, Kay, Mark A., Wu, Joseph C., Lin, Michael Z.
Publicado no Nat Chem Biol (2019)

Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity

por Winters, Ian P., Chiou, Shin-Heng, Paulk, Nicole K., McFarland, Christopher D., Lalgudi, Pranav V., Ma, Rosanna K., Lisowski, Leszek, Connolly, Andrew J., Petrov, Dmitri A., Kay, Mark A., Winslow, Monte M.
Publicado no Nat Commun (2017)

Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors

por Rumachik, Neil G., Malaker, Stacy A., Poweleit, Nicole, Maynard, Lucy H., Adams, Christopher M., Leib, Ryan D., Cirolia, Giana, Thomas, Dennis, Stamnes, Susan, Holt, Kathleen, Sinn, Patrick, May, Andrew P., Paulk, Nicole K.
Publicado no Mol Ther Methods Clin Dev (2020)

In Vivo Selection of Transplanted Hepatocytes by Pharmacological Inhibition of Fumarylacetoacetate Hydrolase in Wild-type Mice

por Paulk, Nicole K, Wursthorn, Karsten, Haft, Annelise, Pelz, Carl, Clarke, Gregory, Newell, Amy H, Olson, Susan B, Harding, Cary O, Finegold, Milton J, Bateman, Raymond L, Witte, John F, McClard, Ronald, Grompe, Markus
Publicado em 2012

Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle

por Paulk, Nicole K., Pekrun, Katja, Charville, Gregory W., Maguire-Nguyen, Katie, Wosczyna, Michael N., Xu, Jianpeng, Zhang, Yue, Lisowski, Leszek, Yoo, Bryan, Vilches-Moure, Jose G., Lee, Gordon K., Shrager, Joseph B., Rando, Thomas A., Kay, Mark A.
Publicado no Mol Ther Methods Clin Dev (2018)

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity

por Paulk, Nicole K., Pekrun, Katja, Zhu, Erhua, Nygaard, Sean, Li, Bin, Xu, Jianpeng, Chu, Kirk, Leborgne, Christian, Dane, Allison P., Haft, Annelise, Zhang, Yue, Zhang, Feijie, Morton, Chris, Valentine, Marcus B., Davidoff, Andrew M., Nathwani, Amit C., Mingozzi, Federico, Grompe, Markus, Alexander, Ian E., Lisowski, Leszek, Kay, Mark A.
Publicado no Mol Ther (2018)

Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase

por Puzzo, Francesco, Colella, Pasqualina, Biferi, Maria G., Bali, Deeksha, Paulk, Nicole K., Vidal, Patrice, Collaud, Fanny, Simon-Sola, Marcelo, Charles, Severine, Hardet, Romain, Leborgne, Christian, Meliani, Amine, Cohen-Tannoudji, Mathilde, Astord, Stephanie, Gjata, Bernard, Sellier, Pauline, van Wittenberghe, Laetitia, Vignaud, Alban, Boisgerault, Florence, Barkats, Martine, Laforet, Pascal, Kay, Mark A., Koeberl, Dwight D., Ronzitti, Giuseppe, Mingozzi, Federico
Publicado no Sci Transl Med (2017)