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Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor

BACKGROUND: Nuclear localization of proteolytically formed intracellular fragment of ErbB4 receptor tyrosine kinase has been shown to promote cell survival, and nuclear localization of ErbB4 receptor has been described in human breast cancer. Tumor necrosis factor alpha converting enzyme (TACE) init...

詳細記述

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書誌詳細
主要な著者: Määttä, Jorma A, Olli, Kaisa, Henttinen, Tiina, Tuittila, Minna T, Elenius, Klaus, Salmivirta, Markku
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636757/
https://ncbi.nlm.nih.gov/pubmed/19171023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-5
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