Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor

BACKGROUND: Nuclear localization of proteolytically formed intracellular fragment of ErbB4 receptor tyrosine kinase has been shown to promote cell survival, and nuclear localization of ErbB4 receptor has been described in human breast cancer. Tumor necrosis factor alpha converting enzyme (TACE) init...

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Détails bibliographiques
Auteurs principaux: Määttä, Jorma A, Olli, Kaisa, Henttinen, Tiina, Tuittila, Minna T, Elenius, Klaus, Salmivirta, Markku
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636757/
https://ncbi.nlm.nih.gov/pubmed/19171023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-5
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