Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor

BACKGROUND: Nuclear localization of proteolytically formed intracellular fragment of ErbB4 receptor tyrosine kinase has been shown to promote cell survival, and nuclear localization of ErbB4 receptor has been described in human breast cancer. Tumor necrosis factor alpha converting enzyme (TACE) init...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Määttä, Jorma A, Olli, Kaisa, Henttinen, Tiina, Tuittila, Minna T, Elenius, Klaus, Salmivirta, Markku
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2009
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636757/
https://ncbi.nlm.nih.gov/pubmed/19171023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-5
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