The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

Medulloblastomas (MBs) are the most common brain tumors in children. Some are thought to originate from cerebellar granule neuron progenitors (GNPs) that fail to undergo normal cell cycle exit and differentiation. Because microRNAs regulate numerous aspects of cellular physiology and development, we...

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Detalhes bibliográficos
Main Authors: Uziel, Tamar, Karginov, Fedor V., Xie, Suqing, Parker, Joel S., Wang, Yong-Dong, Gajjar, Amar, He, Lin, Ellison, David, Gilbertson, Richard J., Hannon, Gregory, Roussel, Martine F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636735/
https://ncbi.nlm.nih.gov/pubmed/19196975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809579106
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