An ABC transporter drives the Sonic Hedgehog pathway contributing to medulloblastoma pathogenesis

Mutations in sonic hedgehog (SHH) signaling promote aberrant proliferation and tumor growth. SHH-medulloblastoma (MB) is among the most frequent brain tumor among children less than three years of age. While key components of the SHH-pathway are well known, we hypothesized that new candidate drivers...

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Pubblicato in:Cancer Res
Autori principali: Wijaya, Juwina, Vo, BaoHan T, Liu, Jingjing, Xu, Beisi, Wu, Gang, Wang, Yao, Peng, Junmin, Zhang, Jin, Janke, Laura J, Orr, Brent A, Yu, Jiyang, Roussel, Martine F, Schuetz, John D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416697/
https://ncbi.nlm.nih.gov/pubmed/31948942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2054
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