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An ABC transporter drives the Sonic Hedgehog pathway contributing to medulloblastoma pathogenesis
Mutations in sonic hedgehog (SHH) signaling promote aberrant proliferation and tumor growth. SHH-medulloblastoma (MB) is among the most frequent brain tumor among children less than three years of age. While key components of the SHH-pathway are well known, we hypothesized that new candidate drivers...
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| 出版年: | Cancer Res |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7416697/ https://ncbi.nlm.nih.gov/pubmed/31948942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2054 |
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