The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

Medulloblastomas (MBs) are the most common brain tumors in children. Some are thought to originate from cerebellar granule neuron progenitors (GNPs) that fail to undergo normal cell cycle exit and differentiation. Because microRNAs regulate numerous aspects of cellular physiology and development, we...

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Hlavní autoři: Uziel, Tamar, Karginov, Fedor V., Xie, Suqing, Parker, Joel S., Wang, Yong-Dong, Gajjar, Amar, He, Lin, Ellison, David, Gilbertson, Richard J., Hannon, Gregory, Roussel, Martine F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636735/
https://ncbi.nlm.nih.gov/pubmed/19196975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809579106
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