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CDK targets Sae2 to control DNA-end resection and homologous recombination
DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous recombination (HR)(1). HR is the most accurate DSB repair mechanism but is generally restricted to the S and G2 phases of the cell cycle, when DNA has been replicated and a sist...
Shranjeno v:
| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635538/ https://ncbi.nlm.nih.gov/pubmed/18716619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07215 |
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