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CDK targets Sae2 to control DNA-end resection and homologous recombination

DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous recombination (HR)(1). HR is the most accurate DSB repair mechanism but is generally restricted to the S and G2 phases of the cell cycle, when DNA has been replicated and a sist...

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Bibliografske podrobnosti
Main Authors: Huertas, Pablo, Cortés-Ledesma, Felipe, Sartori, Alessandro A., Aguilera, Andrés, Jackson, Stephen P.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635538/
https://ncbi.nlm.nih.gov/pubmed/18716619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07215
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