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DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
A single double-strand break (DSB) induced by HO endonuclease triggers both repair by homologous recombination and activation of the Mec1-dependent DNA damage checkpoint in budding yeast(1–6). Here we report that DNA damage checkpoint activation by a DSB requires the cyclin-dependent kinase CDK1 (Cd...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4493751/ https://ncbi.nlm.nih.gov/pubmed/15496928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02964 |
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