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Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination

While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of double-strand break (DSB) repair is exerted at several steps, the key step is DNA end resection, which in Saccharomyces cerevisiae is controlled by the MRX complex and the Sgs1 DNA hel...

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Detalhes bibliográficos
Main Authors: Muñoz-Galván, Sandra, López-Saavedra, Ana, Jackson, Stephen P., Huertas, Pablo, Cortés-Ledesma, Felipe, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561951/
https://ncbi.nlm.nih.gov/pubmed/23254329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1274
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