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Type III restriction enzymes communicate in 1D without looping between their target sites

To cleave DNA, Type III restriction enzymes must communicate the relative orientation of two asymmetric recognition sites over hundreds of base pairs. The basis of this long-distance communication, for which ATP hydrolysis by their helicase domains is required, is poorly understood. Several conflict...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ramanathan, Subramanian P., van Aelst, Kara, Sears, Alice, Peakman, Luke J., Diffin, Fiona M., Szczelkun, Mark D., Seidel, Ralf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633214/
https://ncbi.nlm.nih.gov/pubmed/19181848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807193106
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