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Type III restriction enzymes communicate in 1D without looping between their target sites
To cleave DNA, Type III restriction enzymes must communicate the relative orientation of two asymmetric recognition sites over hundreds of base pairs. The basis of this long-distance communication, for which ATP hydrolysis by their helicase domains is required, is poorly understood. Several conflict...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633214/ https://ncbi.nlm.nih.gov/pubmed/19181848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807193106 |
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