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DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion

DNA cleavage by the Type III Restriction–Modification enzymes requires communication in 1D between two distant indirectly-repeated recognitions sites, yet results in non-specific dsDNA cleavage close to only one of the two sites. To test a recently proposed ATP-triggered DNA sliding model, we addres...

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Bibliografiske detaljer
Main Authors: Schwarz, Friedrich W., van Aelst, Kara, Tóth, Júlia, Seidel, Ralf, Szczelkun, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185417/
https://ncbi.nlm.nih.gov/pubmed/21724613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr502
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