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The helicase-like domains of Type III restriction enzymes trigger long-range diffusion along DNA

Helicases are ubiquitous ATPases with widespread roles in genome metabolism. Here we report a new functionality for ATPases with helicase-like domains, namely that ATP hydrolysis can trigger ATP-independent long-range protein diffusion on DNA in one dimension (1D). Specifically, using single-molecul...

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Detalhes bibliográficos
Main Authors: Schwarz, Friedrich W., Tóth, Júlia, van Aelst, Kara, Cui, Guanshen, Clausing, Sylvia, Szczelkun, Mark D., Seidel, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646237/
https://ncbi.nlm.nih.gov/pubmed/23599494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1231122
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