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Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair

It has previously been shown that transcription greatly enhances recombination in mammalian cells. However, the proteins involved in catalysing this process and the recombination pathways involved in transcription-associated recombination (TAR) are still unknown. It is well established that both the...

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Hlavní autoři: Savolainen, Linda, Helleday, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632912/
https://ncbi.nlm.nih.gov/pubmed/19043071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn971
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