Physical and functional interaction between DDB and XPA in nucleotide excision repair

Damaged DNA-binding protein (DDB), consisting of DDB1 and DDB2 subunits recognizes a wide spectrum of DNA lesions. DDB is dispensable for in vitro nucleotide excision repair (NER) reaction, but stimulates this reaction especially for cyclobutane pyrimidine dimer (CPD). Here we show that DDB directly...

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Bibliografiske detaljer
Main Authors: Wakasugi, Mitsuo, Kasashima, Hiromi, Fukase, Yuko, Imura, Mayumi, Imai, Rika, Yamada, Saki, Cleaver, James E., Matsunaga, Tsukasa
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632899/
https://ncbi.nlm.nih.gov/pubmed/19056823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn964
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