UV radiation-induced SUMOylation of DDB2 regulates nucleotide excision repair

Subunit 2 of DNA damage-binding protein complex (DDB2) is an early sensor of nucleotide excision repair (NER) pathway for eliminating DNA damage induced by UV radiation (UVR) and cisplatin treatments of mammalian cells. DDB2 is modified by ubiquitin and poly(ADP-ribose) (PAR) in response to UVR, and...

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Bibliographic Details
Published in:Carcinogenesis
Main Authors: Han, Chunhua, Zhao, Ran, Kroger, John, He, Jinshan, Wani, Gulzar, Wang, Qi-En, Wani, Altaf A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Biology, Genetics and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446238/
https://ncbi.nlm.nih.gov/pubmed/28981631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx076
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