Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair

Xeroderma pigmentosum group G (XPG) protein is a structure-specific repair endonuclease, which cleaves DNA strands on the 3′ side of the DNA damage during nucleotide excision repair (NER). XPG also plays a crucial role in initiating DNA repair synthesis through recruitment of PCNA to the repair site...

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Publicado en:Cell Cycle
Main Authors: Han, Chunhua, Wani, Gulzar, Zhao, Ran, Qian, Jiang, Sharma, Nidhi, He, Jinshan, Zhu, Qianzheng, Wang, Qi-En, Wani, Altaf A
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614405/
https://ncbi.nlm.nih.gov/pubmed/25483071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.973740
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