p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair

Besides the primary histone acetyltransferase (HAT)-mediated chromatin remodeling function, co-transcriptional factor, p300, is also known to play a distinct role in DNA repair. However, the exact mechanism of p300 function in DNA repair has remained unclear and difficult to discern due to the phosp...

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Detalhes bibliográficos
Main Authors: Wang, Qi-En, Han, Chunhua, Zhao, Ran, Wani, Gulzar, Zhu, Qianzheng, Gong, Li, Battu, Aruna, Racoma, Ira, Sharma, Nidhi, Wani, Altaf A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561975/
https://ncbi.nlm.nih.gov/pubmed/23275565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1312
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