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DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair
The ERCC1-XPF heterodimer is a structure-specific endonuclease and plays multiple roles in various DNA repair pathways including nucleotide excision repair and also telomere maintenance. The dimer formation, which is mediated by their C-terminal helix-hairpin-helix regions, is essential for their en...
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| Veröffentlicht in: | Biochem Biophys Res Commun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6759389/ https://ncbi.nlm.nih.gov/pubmed/31493872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.08.147 |
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