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DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair

The ERCC1-XPF heterodimer is a structure-specific endonuclease and plays multiple roles in various DNA repair pathways including nucleotide excision repair and also telomere maintenance. The dimer formation, which is mediated by their C-terminal helix-hairpin-helix regions, is essential for their en...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Kawara, Hiroaki, Akahori, Ryo, Wakasugi, Mitsuo, Sancar, Aziz, Matsunaga, Tsukasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759389/
https://ncbi.nlm.nih.gov/pubmed/31493872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.08.147
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