Physical and functional interaction between DDB and XPA in nucleotide excision repair

Damaged DNA-binding protein (DDB), consisting of DDB1 and DDB2 subunits recognizes a wide spectrum of DNA lesions. DDB is dispensable for in vitro nucleotide excision repair (NER) reaction, but stimulates this reaction especially for cyclobutane pyrimidine dimer (CPD). Here we show that DDB directly...

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Detalhes bibliográficos
Main Authors: Wakasugi, Mitsuo, Kasashima, Hiromi, Fukase, Yuko, Imura, Mayumi, Imai, Rika, Yamada, Saki, Cleaver, James E., Matsunaga, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632899/
https://ncbi.nlm.nih.gov/pubmed/19056823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn964
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