Physical and functional interaction between DDB and XPA in nucleotide excision repair

Damaged DNA-binding protein (DDB), consisting of DDB1 and DDB2 subunits recognizes a wide spectrum of DNA lesions. DDB is dispensable for in vitro nucleotide excision repair (NER) reaction, but stimulates this reaction especially for cyclobutane pyrimidine dimer (CPD). Here we show that DDB directly...

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Autores principales: Wakasugi, Mitsuo, Kasashima, Hiromi, Fukase, Yuko, Imura, Mayumi, Imai, Rika, Yamada, Saki, Cleaver, James E., Matsunaga, Tsukasa
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632899/
https://ncbi.nlm.nih.gov/pubmed/19056823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn964
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